7-Nights Italy & Amalfi Coast from $6,249

The creative explosion of the Italian Renaissance happened right here, leaving petite Florence more art treasures than most national capitals. View the masterworks of local heroes like Michelangelo and Botticelli, visit countless unforgettable basilicas, then climb up into Brunelleschi's soaring dome to watch the sun set among cypress-clad Tuscan hillsides.

From Naples visitors can explore the rugged Amalfi coast, Italy's most romantic stretch of coastline. Near Amalfi is the resort of Positano, where visitors enjoy strolling through streets and shopping in small boutiques. Take an excursion to legendary Pompeii, an ancient Roman city covered and preserved by the debris from the violent eruption of Mount Vesuvius in 79 A.D. The monuments of this city are considered to be among the finest of any ancient city in Europe, and visitors can spend a day here learning about life in a Roman town during the first century A.D. The Cathedral of San Gennaro, a fine medieval building, has one chapel containing the tomb of Charles of Anjou, while another houses the cathedral's gold and silver treasure. Among the Christian underground burial vaults discovered in an area of suburban heights, the Catacombs of San Gennaro can be visited. Capodimonte Park - a well-kept tropical park - has a royal palace built by Charles III in 1738 that now houses Naples' picture gallery, the National Museum of Capodimonte.